Carla I Tasca Selected Research

Quinolinic Acid

4/2020	Adenosine and NMDA Receptors Modulate Neuroprotection-Induced NMDA Preconditioning in Mice.
10/2018	Role of Phosphatidylinositol-3 Kinase Pathway in NMDA Preconditioning: Different Mechanisms for Seizures and Hippocampal Neuronal Degeneration Induced by Quinolinic Acid.
9/2014	Aloysia gratissima prevents cellular damage induced by glutamatergic excitotoxicity.
7/2013	NMDA preconditioning attenuates cortical and hippocampal seizures induced by intracerebroventricular quinolinic acid infusion.
2/2012	ConBr, a lectin from Canavalia brasiliensis seeds, protects against quinolinic acid-induced seizures in mice.
8/2009	Atorvastatin prevents hippocampal cell death due to quinolinic acid-induced seizures in mice by increasing Akt phosphorylation and glutamate uptake.
1/2008	Quinolinic acid-induced seizures stimulate glutamate uptake into synaptic vesicles from rat brain: effects prevented by guanine-based purines.
4/2005	In vivo quinolinic acid increases synaptosomal glutamate release in rats: reversal by guanosine.

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Carla I Tasca Research Topics

Disease

11	Seizures (Absence Seizure) 04/2020 - 04/2005
8	Ischemia 12/2019 - 06/2002
7	Parkinson Disease (Parkinson's Disease) 01/2018 - 01/2011
6	Alzheimer Disease (Alzheimer's Disease) 10/2020 - 07/2015
6	Mitochondrial Diseases (Mitochondrial Disease) 10/2020 - 01/2011
4	Neuroinflammatory Diseases 11/2021 - 12/2010
3	Mood Disorders (Mood Disorder) 01/2018 - 06/2013
3	Memory Disorders (Memory Loss) 01/2017 - 12/2010
3	Brain Ischemia (Cerebral Ischemia) 12/2016 - 01/2015
3	Inflammation (Inflammations) 08/2013 - 03/2012
3	Epilepsy (Aura) 08/2009 - 04/2005
2	Pain (Aches) 01/2018 - 10/2016
2	Nervous System Diseases (Neurological Disorders) 01/2018 - 04/2015
2	Glioma (Gliomas) 01/2018 - 01/2018
2	Brain Diseases (Brain Disorder) 01/2017 - 10/2016
2	Dyskinesias (Dyskinesia) 01/2017 - 01/2011
2	Hypercholesterolemia 12/2016 - 07/2014
2	Neurodegenerative Diseases (Neurodegenerative Disease) 05/2016 - 09/2011
2	Neuroblastoma 05/2016 - 08/2012
2	Cognitive Dysfunction 07/2015 - 12/2010
2	Depressive Disorder (Melancholia) 07/2013 - 09/2011
2	Brain Injuries (Brain Injury) 06/2013 - 08/2009
1	Disease Progression 10/2020
1	Neoplasms (Cancer) 01/2018
1	Catalepsy 01/2017
1	Anhedonia 01/2017
1	Movement Disorders (Movement Disorder) 01/2017
1	Spinal Cord Injuries (Spinal Cord Injury) 10/2016
1	Stroke (Strokes) 01/2015
1	Temporal Lobe Epilepsy 05/2013
1	Status Epilepticus (Complex Partial Status Epilepticus) 05/2013
1	Bipolar Disorder (Manic Depressive Psychosis) 04/2012
1	Psychotic Disorders (Schizoaffective Disorder) 01/2011
1	Brain Concussion (Cerebral Concussion) 05/2010

Drug/Important Bio-Agent (IBA)

17	Glutamic Acid (Glutamate)FDA Link 10/2020 - 04/2005
10	Atorvastatin (Lipitor)FDA Link 11/2021 - 08/2009
10	Neuroprotective AgentsIBA 12/2019 - 06/2002
9	GuanosineIBA 12/2019 - 04/2005
8	Quinolinic AcidIBA 04/2020 - 04/2005
6	N-Methylaspartate (NMDA)IBA 04/2020 - 01/2008
5	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2018 - 06/2013
5	Glucose (Dextrose)FDA LinkGeneric 12/2016 - 04/2006
5	Oxygen (Dioxygen)IBA 12/2016 - 04/2006
4	Peptides (Polypeptides)IBA 10/2020 - 12/2010
4	GuanineIBA 12/2019 - 01/2008
4	Neurotransmitter Agents (Neurotransmitter)IBA 12/2019 - 10/2016
4	1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA 06/2013 - 01/2011
3	Antidepressive Agents (Antidepressants)IBA 01/2017 - 09/2011
3	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 05/2016 - 05/2010
2	Amyloid (Amyloid Fibrils)IBA 10/2020 - 07/2015
2	Purinergic P1 Receptors (Adenosine Receptor)IBA 04/2020 - 08/2013
2	PurinesIBA 12/2019 - 01/2008
2	Oxidopamine (6 Hydroxydopamine)IBA 12/2016 - 01/2014
2	CreatineIBA 05/2016 - 01/2014
2	Dizocilpine Maleate (Dizocilpine)IBA 05/2016 - 01/2008
2	AntioxidantsIBA 07/2015 - 04/2006
2	Arginine (L-Arginine)FDA Link 04/2015 - 09/2011
2	ConvulsantsIBA 05/2013 - 01/2008
2	NucleosidesIBA 08/2012 - 04/2005
1	Nerve Growth Factors (Neurotrophins)IBA 10/2020
1	ZM 241385 (ZM241385)IBA 04/2020
1	2- cyclohexylidenhydrazo- 4- phenyl- thiazoleIBA 04/2020
1	Purine NucleosidesIBA 12/2019
1	Adenosine (Adenocard)FDA LinkGeneric 12/2019
1	Phosphotransferases (Kinase)IBA 10/2018
1	fluoro jadeIBA 10/2018
1	Dihydrotachysterol (AT 10)IBA 01/2018
1	Pharmaceutical PreparationsIBA 01/2018
1	Biological ProductsIBA 01/2018
1	Temozolomide (Temodar)FDA LinkGeneric 01/2018
1	Reserpine (Serpasil)FDA Link 01/2017
1	Fluoxetine (Prozac)FDA LinkGeneric 01/2017
1	purineIBA 01/2017
1	Amyloid beta-PeptidesIBA 01/2017
1	Levodopa (L Dopa)FDA LinkGeneric 01/2017
1	MelatoninIBA 12/2016
1	Reactive Oxygen Species (Oxygen Radicals)IBA 12/2016
1	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 05/2016
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 04/2015
1	Purinergic Receptors (Receptors, Purine)IBA 03/2015
1	Thiobarbituric Acid Reactive SubstancesIBA 03/2015
1	Docosahexaenoic AcidsIBA 03/2015
1	Protective AgentsIBA 09/2014
1	Excitatory Amino AcidsIBA 09/2014
1	NF-kappa B (NF-kB)IBA 08/2013
1	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 08/2013
1	Adrenergic Receptors (Adrenergic Receptor)IBA 07/2013
1	Antiparkinson Agents (Antiparkinsonian Agents)IBA 06/2013
1	Pilocarpine (Ocusert)FDA LinkGeneric 05/2013
1	Heme (Haem)IBA 08/2012
1	LithiumIBA 04/2012
1	Valproic Acid (Depakote)FDA LinkGeneric 04/2012
1	ferulic acid (sodium ferulate)IBA 03/2012
1	Canavalia lectinIBA 02/2012
1	LectinsIBA 02/2012

Therapy/Procedure

2	Therapeutics 05/2016 - 01/2011
1	Drug Therapy (Chemotherapy) 01/2018
1	Complementary Therapies (Alternative Medicine) 01/2018
1	Intranasal Administration 01/2011
1	Anesthesia 05/2010